Sapphire not opening

I recently changed the USB drive i as using with my ATV to having Network access using nitoTV, now Sapphire does not even open. I tried doing a fresh install of ATV version 3.5.4 but i get the same issue, Sapphire still does not open. Has anyone ever encountered this issue with Sapphire or know how to solve it.

The only thing I now to try is to remove the Application Support folder for Sapphire. You can find my previous mention of this: