Plex not playing videos / HTTP 500 error

Currently, Infuse will direct stream all content from the Plex server in the original format, without transcoding. This means the upload bandwidth settings will need to be set high enough (around 2x the average bitrate) for the videos being played. If this is not done, then Plex would not be able to deliver enough of the stream for Infuse to play, and could result in errors like this.

There are also cases where Plex may be directing traffic through its relay service which has a rather low bandwidth limit. I don’t believe Plex as an official way to disable this service, but there are some suggestions on doing this.