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James, since this morning my Infuse will not play videos anymore from my AppleTV. All the other apps work just fine. My AppleTV is connected with CAT 6 cable to router (XR500 Netgear) and USB HDD is connected to router. Tried to reboot Router, Reset Router, to NO avail. Tried rebooting AppleTV, NO avail. Uninstalled Infuse and re-installed, NO avail.

Welcome to the forum!

A little more info may help.
Which ATV 4 or 4K(generation 5)?
What tvOS version?
What version number of Infuse?

What protocol are you connectiing with? SMB, DLNA, FTP, etc?

Also do you have an iPhone/iPad that is also having the same problems or is this only on Apple TV?