I have the same problem.
Infuse Version 7.1 (7.1.3799) on my iMac.
I have a HD connected to an AirPort Extreme. SMB.
I can play the movie fine at first and when I pause and come back to it later. I got an error message:
" An error occurred An error occurred loading this content."
And I can’t play the movie anymore on Infuse using my iPhone, iMac or AppleTV.
The file is corrupted as I can’t even play it on my iMac using VLC.
It happened several times with mkv and mp4.