Dedicated Media Drive Recommended for Infuse?

Been thinking about setting up a NAS. Would there be benefits to setting aside a dedicated drive for Infuse use and using the second drive bay for other short and long term storage data (photos, documents, etc.)? Or, would keeping all data on one large drive and using the other drive as a backup be smarter? I know I can get NAS devices with more bays, but I’m trying to stay within budget. Thanks for any insight.