I tried Plex Pass and running it on a Windows 10 machine. It looked great but I had all sorts of issues… Most notably with bigger files and running 4K material. Some files it just wouldn’t run. Kept getting an error message that I didn’t have enough bandwidth (on a cabled connection). I did a search for it and it seems it’s one of those errors they never fixed, so if you get it you’re f****** basically. So I went back to infuse.
No issues with Infuse at all in this department. I have to say having tried quite a few solutions now, infuse is the best for me with ease of use and it just runs everything that I ask it to.